Table 3.

Time-to-event analysis of the cumulative incidence rate of SREs and total number of SREs by SRE type.

Cumulative follow-up time (median follow-up: 25.7 months)				Type of SRE
	Any SRE			Spinal cord compression			Pathologic fracture			Radiation to bone
	Patients with SREs, %	SREs, n	Incidence rate per 100 PYs	Patients with event, %	Events, n	Incidence rate per 100 PYs	Patients with event, %	Events, n	Incidence rate per 100 PYs	Patients with event, %	Events, n	Incidence rate per 100 PYs
3 months	6.1	25	29.6	0	0	0	5.0	19	22.5	1.7	6	7.1
6 months	14.9	77	45.6	0	0	0	12.0	61	36.1	3.8	16	9.5
9 months	19.0	116	45.8	1.2	4	1.6	14.9	95	37.5	4.1	17	6.7
12 months	23.0	156	46.1	1.7	6	1.8	18.1	128	37.9	5.0	22	6.5
15 months	24.5	177	42.4	2.3	8	1.9	18.7	143	34.2	5.8	26	6.2
18 months	28.0	204	41.8	2.6	9	1.8	21.6	163	33.4	6.7	32	6.6
21 months	29.2	224	40.8	2.9	10	1.8	22.4	179	32.6	7.0	35	6.4
24 months	30.6	243	40.4	3.5	14	2.3	22.7	189	31.4	7.6	40	6.7
60 months	34.1	311	38.9	3.5	16	2.0	26.8	248	31.1	8.2	47	5.9

PYs, person-years; SRE, skeletal-related event.

All surgery to bone events were reclassified as either spinal cord compression or pathologic fracture due to all events occurring within 21 days of each other.