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. 2019 Jan 11;17:169–176. doi: 10.1016/j.bbrep.2019.01.003

Fig. 2.

Fig. 2

Increased level of renal oxidative stress in Aqp11-/- mice. A-B: Immunoblot analysis of the renal protein carbonyl content in WT and Aqp11-/- mice. A: A typical immunoblot. The bands over a wide range indicate protein carbonyl. P: Positive control (oxidative bovine serum albumin). B: Quantitative analysis of renal protein carbonyl content. Numbers in parentheses indicate the number of animals tested. Values are expressed as percentages of the mean value in WT mice. * P < 0.05 compared with WT mice. C-D: Typical results of immunohistochemistry for renal 8-OHdG in WT (C) and Aqp11-/- (D) mice. Brown color indicates the presence of 8-OHdG. Scale bar: 50 µm.