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Effects of MI fibroblast secretome on in vitro endothelial cell tube formation. Day 0 and MI day 3 cardiac fibroblast secretome increased, while MI day 7 secretome decreased angiogenic variables relative to the effects of the day 0 secretome. MI day 7 secretome effects were inhibited by a Thbs1 blocking antibody. Scale bar = 200 µm. n = 3 per group. *p < 0.05 versus basal, #p < 0.05 versus day 0, $p < 0.05 versus MI day 7
