Fig. 3.

Quality of data collected. Legend (see also Table 2 for more details). Score_UPDATE means adherence to periodic central database update; Score_N._Pts_year means sample size by center; Score:_Pts_with FUP ≥ 5 years means sample size by center with prospective clinical follow-up ≥5 years; Score:_active Pts means patients in active status, i.e., at least one visit and/or contact with the center in the last 2 years; Score:_VISIT every 6 months means semi-annual visit rates; Score:_EDSS every 6 months means semi-annual EDSS assessment rates; Score:_I°visit_within_I° yr from onset means first visit within 2 year of the disease onset.