Table 2.
Ultrasonographic characteristics and BRAFV600E status of PTC patients with and without cervical LNM.
| Parameters | Characteristics | Metastasis no. (%) | X2/t/U value | P value | |
|---|---|---|---|---|---|
| Yes (n = 108) | No (n = 172) | ||||
| Multifocality | Yes | 40 (49.4) | 41 (50.6) | X2 = 5.622 | 0.018 |
| No (Single) | 68 (34.2) | 131 (65.8) | |||
| Size, cm | 1.46 ± 0.85 | 0.87 ± 0.40 | t = 7.835 | <0.001 | |
| Shape | Regular | 23 (25.0) | 69 (75.0) | X2 = 10.651 | 0.001 |
| Irregular | 85 (45.2) | 103 (54.8) | |||
| Margin | Well-defined | 24 (29.3) | 58 (70.7) | X2 = 4.236 | 0.040 |
| Ill-defined | 84 (42.4) | 114 (57.6) | |||
| Echogenicity | Homogeneous | 81 (33.5) | 161 (66.5) | X2 = 19.577 | <0.001 |
| Heterogeneous | 27 (71.0) | 11 (29.0) | |||
| Hypoechoic | 101 (38.4) | 162 (61.6) | X2 = 0.560 | 0.972 | |
| Marked-hypoechoic | 5 (41.7) | 7 (58.3) | |||
| Hyper/iso-echoic | 2 (40) | 3 (60) | |||
| Calcification | Absent | 23 (23.5) | 75 (76.5) | X2 = 14.896 | 0.001 |
| Macro-calcification | 3 (60) | 2 (40.0) | |||
| Micro-calcification | 82 (46.3) | 95 (53.7) | |||
| CDFI | Rich | 31 (77.5) | 9 (22.5) | X2 = 29.847 | <0.001 |
| Not rich | 77 (32.1) | 163 (67.9) | |||
| US-LNM | Yes | 69 (94.5) | 4 (5.5) | X2 = 130.455 | <0.001 |
| No | 39 (18.8) | 168 (81.2) | |||
| Taller than wide | >1 | 68 (39.3) | 105 (60.7) | X2 = 0.103 | 0.748 |
| ≤1 | 40 (37.4) | 67 (62.6) | |||
| Distance to capsule | ≤2 mm | 100 (49.0) | 104 (51) | X2 = 34.627 | <0.001 |
| >2 mm | 8 (10.5) | 68 (89.5) | |||
| Diffuse disease | Yes | 16 (14.8) | 45 (26.2) | X2 = 5.014 | 0.025 |
| No | 92 (85.2) | 127 (73.8) | |||
| BRAFV600E mutation | Yes | 85 (37.6) | 141 (62.4) | X2 = 0.457 | 0.499 |
| No | 23 (42.6) | 31 (57.4) | |||