Table 2.
Differential metabolites between FH and PH in exploratory and validation sets
| Metabolites | Exploratory set (n = 46) | Validation set (n = 40) | |||
|---|---|---|---|---|---|
| VIP | FC | P | FC | P | |
| 2-Deoxytetronic acid | 2.82 | 0.35 | <0.001 | 1.02 | 0.829 |
| Sophorose | 2.45 | 0.51 | 0.001 | 1.03 | 0.626 |
| Tagatose | 2.39 | 0.46 | <0.001 | 1.06 | 0.465 |
| Glucoheptonic acid | 2.34 | 0.48 | 0.001 | 0.89 | 0.822 |
| Mannose | 2.06 | 0.83 | 0.006 | 0.94 | 0.040 |
| AICAR | 2.05 | 0.86 | 0.022 | 0.68 | 0.003 |
| Phenyl beta-d-glucopyranoside | 1.90 | 0.50 | 0.001 | 0.98 | 0.822 |
| Uridine | 1.74 | 0.55 | 0.016 | 0.65 | 0.843 |
| 3,5-Dihydroxyphenylglycine | 1.33 | 0.62 | 0.040 | 1.12 | 0.705 |
| Palmitic acid | 1.14 | 0.80 | 0.047 | 1.02 | 0.850 |
AICAR 5-aminoimidazole-4-carboxamide ribonucleotide, VIP variable importance projection value, FC fold change (the peak intensity of metabolite in PH divided by that in FH)