Table 3.
The characteristics of the 87 subjects assayed with ELISA
| Variable | NC | FH | PH | P |
|---|---|---|---|---|
| n (male/female) | 15/21 | 15/7 | 16/13 | 0.139 |
| Age (years) | 49.6 ± 10.5 | 50.3 ± 8.6 | 51.9 ± 9.4 | 0.616 |
| BMI (kg/m2) | 25.0 ± 2.6 | 25.9 ± 3.6 | 25.5 ± 3.3 | 0.588 |
| HbA1c (%) | 5.7 ± 0.4 | 6.2 ± 0.5* | 6.2 ± 0.6* | <0.001 |
| FPG (mmol/L) | 5.5 ± 0.5 | 7.3 ± 0.5* | 6.0 ± 0.6*† | <0.001 |
| 2-h PG (mmol/L) | 8.2 ± 1.8 | 8.7 ± 2.1 | 12.8 ± 1.3*† | <0.001 |
| FINS (mU/L) | 9.9 ± 3.0 | 12.9 ± 7.7 | 10.4 ± 4.3 | 0.076 |
| 2-h INS (mU/L) | 93.2 ± 41.9 | 95.6 ± 66.8 | 100.5 ± 57.3 | 0.863 |
| HOMA-B | 103.1 ± 40.0 | 69.2 ± 41.3* | 89.6 ± 44.1 | 0.014 |
| HOMA-IR | 2.4 ± 0.8 | 4.2 ± 2.5* | 2.8 ± 1.2† | <0.001 |
| Cederholm index | 43.7 ± 11.3 | 40.1 ± 12.2 | 28.6 ± 5.0*† | <0.001 |
| Mannose (pg/ml) | 409.2 ± 108.5 | 466.0 ± 179.3 | 390.1 ± 140.2 | 0.130 |
| AICAR (pg/ml) | 372.8 ± 90.9 | 523.5 ± 164.8* | 512.1 ± 186.0* | <0.001 |
NC normal control, FH fasting hyperglycemia, PH post-load hyperglycemia, BMI body mass index, FPG fasting plasma glucose, 2-h PG 2-h plasma glucose, HbA1c glycated hemoglobin, FINS fasting insulin, 2-h INS 2-h insulin, HOMA-IR the homeostasis model assessment for insulin resistance, HOMA-B the homeostasis model assessment for beta cell function
*P < 0.05 compared with NC after Bonferroni correction
†P < 0.05 compared with FH after Bonferroni correction