Table 2.
Dynamic vessel analyzer parameters in affected subjects and controls.
| AD | MCI | Controls | |
|---|---|---|---|
| Dynamic Analysis | |||
| Arterial dilation (%) | 0.77 ± 2.06 | 2.84 ± 2.18 | 3.53 ± 1.25 |
| 0.045* | 0.002* | ||
| — | 1.0† | ||
| Arterial constriction (%) | 0.59 ± 0.88 | 0.55 ± 1.28 | −0.33 ± 1.17 |
| 1.0* | 0.163* | ||
| 0.199† | |||
| Reaction amplitude (%) | 0.21 ± 1.80 | 2.29 ± 1.81 | 3.86 ± 1.94 |
| 0.038* | <0.0001* | ||
| 0.048† | |||
| Venous dilation (%) | 2.84 ± 1.56 | 3.45 ± 1.96 | 3.37 ± 1.81 |
| 1.0* | 0.833* | ||
| 1.0† | |||
| Static Analysis | |||
| AVR | 0.92 ± 0.10 | 0.83 ± 0.10 | 0.89 ± 0.06 |
| 0.070* | 1.0* | ||
| — | 0.236† | ||
| CRAE | 189.81 ± 25.18 | 177.94 ± 26.92 | 186.77 ± 23.63 |
| 0.924* | 1.0* | ||
| 1.0† | |||
| CRVE | 208.04 ± 28.31 | 213.78 ± 16.60 | 207.31 ± 16.53 |
| 1.0* | 1.0* | ||
| 1.0† | |||
*,†ANOVA test with Bonferroni post-hoc *Comparison versus AD; †Comparison versus MCI. Data are presented as mean ± SD (standard deviation).
AD: Alzheimer’s disease; MCI: mild cognitive impairment; AVR: artery-vein ratio; CRAE: central retinal artery equivalent; CRVE: central retinal vein equivalent.