Fig. 8.

pY658VE-cadherin represses the binding of kaiso to their target genes CCND1 and Wnt 11: c, d In vitro angiogenesis assay with Matrigel in MUM 2B showed the effect of siCCND1 or siWNT11, d images were acquired using an Olympus CKX41 microscope (bars 50 μm) and the formation of tube-like structures was then quantified by Wimasis program. Each treatment was performed in triplicate, and the experiment was independently repeated at least three times. a, b siRNA of CCND1 and WNT 11 was confirmed by qPCR