Table 2.
Kaplan-Meier analysis of factors associated with OS in the entire cohort.
| Variable | Mean OS (months) | Median OS (months) | P |
|---|---|---|---|
| Age (years) | 0.843 | ||
| ≤ 58.0† | 82.3 | 37.0 | |
| > 58.0 | 82.0 | 46.0 | |
| Sex | 0.275 | ||
| Male | 79.7 | 36.0 | |
| Female | 83.4 | 56.0 | |
| T status | 0.001 | ||
| T1 | 133.7 | NR | |
| T2 | 85.6 | 56 | |
| T3 | 48.3 | 21 | |
| T4 | 44.6 | 22 | |
| N status | 0.009 | ||
| N0 | 100.9 | 101 | |
| N1 | 87.9 | 69 | |
| N2 | 57.1 | 22 | |
| N3 | 42.2 | 20 | |
| M status | 0.116 | ||
| M0 | 85.2 | 47.0 | |
| M1 | 34.5 | 20.0 | |
| TNM Staging | 0.004 | ||
| I | 110.6 | 113 | |
| II | 80.0 | 69 | |
| III | 61.3 | 28 | |
| IV | 34.5 | 20 | |
| Smoking | 0.283 | ||
| Yes | 78.6 | 29 | |
| No | 82.2 | 56 | |
| CD3+ TILs | 0.891 | ||
| Occurrence | 81.5 | 40 | |
| No occurrence | 82.2 | 56 | |
| CD8+ TILs | 0.382 | ||
| Occurrence | 82.7 | 43.0 | |
| No occurrence | 77.6 | 43.0 | |
| IDO | <0.001 | ||
| High | 113.5 | 163 | |
| Low | 62.6 | 32 | |
| Treatments | |||
| Radical resection | 86.2 | 50 | 0.105 |
| No radical resection | 47.1 | 26 |
†Median age; OS, overall survival; TILs, tumor-infiltrating lymphocytes; IDO, indoleamine 2,3-dioxygenase.