Table 1.
Associations of Plasma GXM, Lam, and Immunoglobulin Levels With CrAg Status
| Univariate Analysisa | Multiple Regressionb | ||||
|---|---|---|---|---|---|
| CrAg+, Median (IQR) | CrAg-, Median (IQR) | P Value | Coefficient | P Value | |
| IgM | 951 (1066) | 785 (408) | .001 | .296 | 0 |
| IgG1 | 8165 (6275) | 7246 (5498) | .074 | .048 | .525 |
| IgG2 | 2280 (2252) | 1281 (1733) | 1.3e-5 | .598 | .001 |
| GXM-IgM | 110 (229) | 155 (332) | .044 | –.335 | .08 |
| GXM-IgG | 331 (448) | 131 (357) | .006 | .448 | .012 |
| Lam-IgM | 115 (229) | 153 (428) | .006 | –.448 | .005 |
| Lam-IgG | 265 (317) | 364 (689) | .004 | –.39 | .003 |
Abbreviations: CrAg, cryptococcal antigen; GXM, glucuronoxylomannan; IgG, immunoglobulin G; IgM, immunoglobulin M; IQR, interquartile range; Lam, Laminarin.
aWilcoxon rank test.
bRegression: log-transformed levels of antibodies compared between CrAg+ and CrAg- participants with adjustment for age, sex, and logCD4