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. 2018 Nov 26;29(24):2946–2958. doi: 10.1091/mbc.E18-05-0305

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© 2018 Saito-Reis et al. “ASCB®,” “The American Society for Cell Biology®,” and “Molecular Biology of the Cell®” are registered trademarks of The American Society for Cell Biology.

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FIGURE 3: — CD82KO HSPCs demonstrate decreased bone marrow homing. (A) Experimental scheme for the competitive homing experiment. (B) The percentage of total bone marrow and (C) of lineage-negative donor cells homed within the blood and bone marrow 16 h postinjection. Donor cell chimerism (WT, CD45.1 and CD82KO, CD45.2) status measured via flow cytometry. Error bars, SEM; n = 8–12 mice per strain (*p < 0.05, ***p < 0.001, and ****p < 0.0001). (D) Experimental scheme for the noncompetitive homing experiment. (E) The percentage of total bone marrow homed within the blood and bone marrow 16 h postinjection. Donor cell chimerism (CD45.2) status measured via flow cytometry. Error bars, SEM; n = 5–7 mice per strain (*p < 0.05 and ****p < 0.0001).