Table 2.
Univariate and Multivariate analysis of factors associated with OS
| Variables | Univariate Analysis | Multivariate Analysis | |||||
|---|---|---|---|---|---|---|---|
| HR | 95% CI | P | HR | 95% CI | P | ||
| Gender (female vs. male) | 0.789 | 0.526-1.183 | 0.251 | ||||
| Smoking status (non-smokers vs. smokers) | 0.779 | 0.543-1.118 | 0.175 | ||||
| Differentiation(Poor/Moderate vs. Well) | 3.889 | 1.235-12.24 | 0.020 | 0.454 | 0.141-1.463 | 0.186 | |
| Lymph node metastasis(Yes vs. No) | 3.042 | 2.103-4.399 | <0.001 | 0.482 | 0.311-0.748 | 0.001 | |
| Tumor size(≥3cm vs. <3cm) | 2.755 | 1.758-4.318 | <0.001 | 0.480 | 0.302-0.763 | 0.002 | |
| Tumor stage (Ⅲ-IV vs. Ⅰ-Ⅱ) | 2.771 | 1.922-3.993 | <0.001 | 0.640 | 0.413-0.992 | 0.046 | |
| Calpain 2 level(high vs. low) | 1.857 | 1.280-2.694 | 0.001 | 0.684 | 0.474-0.988 | 0.043 | |
Abbreviations: OS, overall survival; 95%CI, 95% confidence interval; HR, hazard ratio.