Table IV.

Reported genome-wide significance SNPs from traditional GWAS with critical value of 5×10⁻⁸ of the PLP trait in the TSS from Carter et al. [2015] and ComPaSS-GWAS selected SNPs.

SNP	Chr	Mb	MAF	GWAS p-value	ComPaSS-GWAS Score		ALPL	Association reported prior to Carter et al. [2015]
					α = 1×10−3	α = 1×10−4
rs1780324	1	21.694	0.49	1.3×10−11	0.95†	0.84*	Intergenic	Yuan et al. [2008]
rs1697421	1	21.696	0.49	3.5×10−11	0.94†	0.77*	Intergenic	Keene et al. [2014]
rs1780321	1	21.697	0.33	2.8×10−12	0.98†	0.87*	Intergenic
rs4021228	1	21.736	0.47	4.8×10−9	0.83†	0.33	Intronic
rs1780316	1	21.762	0.07	8.7×10−9	0.72†	0.16	Exonic	Keene et al. [2014]
rs1256335	1	21.763	0.22	5.0×10−14	1.00†	0.98*	Intronic	Harza et al. [2009]
rs2275370	1	21.773	0.21	1.8×10−9	0.78†	0.33	Intronic
rs1772719	1	21.777	0.23	2.5×10−16	1.00†	1.00*	UTR3
rs1772720	1	21.778	0.08	8.8×10−10	0.86†	0.46	Downstream

^†selected for ComPaSS-GWAS parameter set α = 1×10⁻³ and η = 0.6

^*selected for ComPaSS-GWAS parameter set α = 1×10⁻⁴ and η = 0.5