Skip to main content
. Author manuscript; available in PMC: 2019 Dec 1.
Published in final edited form as: Biomech Model Mechanobiol. 2018 Jul 12;17(6):1569–1580. doi: 10.1007/s10237-018-1044-5

Fig. 1. Agent-based model overview.

Fig. 1

(A) 3000 fibroblasts were randomly dispersed across a 1mm × 1mm array of collagen fibers. Fibroblasts were each represented as a disc of 5 μm radius and orientation between −180° and 180°, with 0° corresponding to the direction of global tissue extension. Collagen fibers were represented as a grid of 10μm × 10μm elements, each containing a distribution of fibers oriented in 5° bins from −90° to 90°; the plots indicate the mean fiber angle for each bin. (B) The healing structure was remodeled as each fibroblast iteratively reoriented, migrated, deposited collagen, and removed collagen, according to the prescribed sequence shown.