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. Author manuscript; available in PMC: 2019 Mar 19.
Published in final edited form as: Curr Top Microbiol Immunol. 2018;418:143–184. doi: 10.1007/82_2018_96

Figure 4. Wzx/Wzy polysaccharide pathway: Genetic basis and biosynthesis model for UPP.

Figure 4.

Predicted localization and mechanism of biosynthesis for UPP in A. tumefaciens based on Wzx-Wzy generalized model (Cuthbertson et al. 2009). Branched green filament of diamonds is meant to depict the polysaccharide strand. The black square on some residues is putative acetylation. The Wzb/c protein may hydrolyze ATP to power polymerization. Upp protein names and the general Wzx-Wzy components are indicated in the figure. Black squiggle on the polysaccharide subunit is the undecaprenyl phosphate. Gene colors match protein colors in the diagram; upp gene names above and corresponding Wzx-Wzy components below (AcTrans – acetyltransferase; GT glycosyl transferase). Assembled UPP structure is represented by green cross-hatched oval outside cell, and the diamond headed lines are putative linkages to the cell pole surface. OM, outer membrane; PG, peptidoglycan; IM, inner membrane.