Table 3.
Physical wellbeing (range: 0-28) |
Functional wellbeing (range: 0-28) |
Ovarian cancer-specific (range: 14-44) |
TOI (range: 22-100) |
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---|---|---|---|---|---|---|---|---|---|---|---|---|
est. | SE | p | est. | SE | p | est. | SE | p | est. | SE | p | |
Individual-level factors | ||||||||||||
Race (other v. white) | 0.36 | 0.65 | 0.58 | 0.63 | 0.78 | 0.42 | −0.02 | 0.77 | 0.98 | 0.97 | 1.91 | 0.61 |
Age group (65+ v. <65 years) | 0.31 | 0.37 | 0.41 | −0.20 | 0.45 | 0.65 | −0.30 | 0.44 | 0.49 | −0.18 | 1.10 | 0.87 |
Insurance type (ref: private insurance) | ||||||||||||
Public insurance | −1.00 | 0.49 | 0.04 | −1.29 | 0.59 | 0.03 | −1.60 | 0.59 | 0.01 | −3.81 | 1.46 | 0.01 |
Other | −1.93 | 0.63 | <.01 | −1.98 | 0.76 | 0.01 | −1.66 | 0.75 | 0.03 | −5.51 | 1.86 | <.01 |
Stage (IV v. III) | 0.17 | 0.36 | 0.64 | −0.48 | 0.44 | 0.27 | −0.42 | 0.43 | 0.33 | −0.61 | 1.07 | 0.57 |
Adverse eventsa (yes v. no) | −0.34 | 0.32 | 0.28 | −0.57 | 0.39 | 0.14 | −0.52 | 0.38 | 0.17 | −1.33 | 0.94 | 0.15 |
Contextual factors | ||||||||||||
Median household income | Overall p | 0.91 | Overall p | 0.45 | Overall p | 0.14 | Overall p | 0.35 | ||||
1 (lowest income) | (ref) | (ref) | (ref) | (ref) | ||||||||
2 | 0.14 | 0.48 | 0.76 | 0.81 | 0.58 | 0.16 | 1.04 | 0.58 | 0.07 | 2.03 | 1.43 | 0.16 |
3 | −0.05 | 0.57 | 0.93 | 0.09 | 0.68 | 0.90 | −0.10 | 0.68 | 0.88 | −0.05 | 1.68 | 0.98 |
4 (highest income) | 0.27 | 0.65 | 0.68 | 0.27 | 0.78 | 0.73 | 0.34 | 0.80 | 0.67 | 0.96 | 1.94 | 0.62 |
Adults with a high school degree or higher | Overall p | 0.33 | Overall p | 0.26 | Overall p | 0.06 | Overall p | 0.12 | ||||
1 (lowest education) | (ref) | (ref) | (ref) | (ref) | ||||||||
2 | 0.63 | 0.49 | 0.20 | 0.66 | 0.60 | 0.27 | 0.34 | 0.59 | 0.56 | 1.60 | 1.46 | 0.27 |
3 | 0.04 | 0.57 | 0.94 | 0.16 | 0.69 | 0.82 | −0.17 | 0.69 | 0.81 | −0.07 | 1.69 | 0.97 |
4 (highest education) | 0.67 | 0.65 | 0.30 | 1.14 | 0.78 | 0.15 | 1.35 | 0.78 | 0.08 | 3.05 | 1.92 | 0.11 |
Residents who are non-white race | Overall p | 0.40 | Overall p | 0.82 | Overall p | 0.50 | Overall p | 0.73 | ||||
1 (lowest non-white %) | (ref) | (ref) | (ref) | (ref) | ||||||||
2 | 0.30 | 0.45 | 0.50 | 0.27 | 0.54 | 0.62 | 0.04 | 0.54 | 0.94 | 0.59 | 1.33 | 0.66 |
3 | −0.35 | 0.46 | 0.44 | 0.28 | 0.55 | 0.60 | −0.69 | 0.55 | 0.21 | −0.45 | 1.35 | 0.58 |
4 (highest non-white %) | 0.32 | 0.50 | 0.52 | 0.58 | 0.60 | 0.34 | −0.37 | 0.61 | 0.55 | 0.51 | 1.49 | 0.73 |
Travel distance (quartiles) | Overall p | 0.23 | Overall p | 0.55 | Overall p | 0.31 | Overall p | 0.62 | ||||
1 (least distance) | (ref) | (ref) | (ref) | (ref) | ||||||||
2 | −0.92 | 0.45 | 0.04 | 0.00 | 0.55 | 1.00 | −0.81 | 0.54 | 0.13 | −1.75 | 1.34 | 0.19 |
3 | −0.68 | 0.47 | 0.14 | 0.62 | 0.56 | 0.27 | −0.55 | 0.56 | 0.32 | −0.65 | 1.38 | 0.64 |
4 (most distance) | −0.51 | 0.47 | 0.28 | −0.10 | 0.57 | 0.87 | 0.12 | 0.57 | 0.83 | −0.54 | 1.40 | 0.70 |
Grades 3, 4, or 5, excluding hematological events.
Note. Each column represents one model. Models account for clustering by medical institution and region of the country. Models control for baseline levels of the respective HRQOL measure. Overall p-values reflect statistical significance of the joint associations of the four levels of the respective contextual factor. TOI=trial outcomes index.