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. Author manuscript; available in PMC: 2019 Dec 1.
Published in final edited form as: Chromosoma. 2018 Jul 12;127(4):405–420. doi: 10.1007/s00412-018-0677-6

Fig. 2. The major repair pathways.

Fig. 2.

DNA DSBs are repaired by nonhomologous end-joining (NHEJ) or by homology-dependent repair (HDR). When a DNA donor is present, it can be integrated, as shown for HDR. In the absence of a DNA donor, small insertions and deletions (indels) are created by NHEJ.