Table 3. Summary of detected nucleotide variations and comparison overweight patients (BMI 25 – < 30) with healthy weight/control group (BMI 18.5 – < 25).
| Genotypes | Patients, n = 65 | Patients, % | p-value | Odds ratio |
|---|---|---|---|---|
| A-A (FTO) | 6 | 10 | < 0.005 | 4.269 |
| T-T (FTO) | 28 | 43 | < 0.005 | 0.171 |
| A-T (FTO) | 31 | 47 | ns | 1.224 |
| T-T (MC4R) | 14 | 22 | ns | 0.493 |
| C-C (MC4R) | 21 | 32 | 0.077 | 1.889 |
| C-T (MC4R) | 30 | 46 | ns | 1.291 |
A p-value < 0.005 was considered statistically significant; ns: non-significant. BMI: body mass index; FTO: fat mass and obesity-associated;
MC4R: melanocortin-4 receptor.