Table 4. Summary of detected nucleotide variations and comparison obese patients (BMI > 30) with healthy weight/control group (BMI 18.5 – < 25).

Genotypes	Patients, n = 65	Patients, %	p-value	Odds ratio
A-A (FTO)	15	23	< 0.005	6.927
T-T (FTO)	29	45	< 0.005	0.244
A-T (FTO)	21	32	ns	0.624
T-T (MC4R)	27	42	0.064	0.587
C-C (MC4R)	17	26	ns	1.079
C-T (MC4R)	21	32	ns	1.582

BMI: body mass index; FTO: fat mass and obesity-associated; MC4R: melanocortin-4 receptor; ns: non-significant.