Table 1. Clinical, laboratory, and operative characteristics of total studied patients (n = 542). Comparison between low TI and high TI groups was made.
| Parameter | Total, % (n = 542) |
Low TI (≤ 6.5 µg/L), % (n = 164) |
High TI (> 6.5 µg/L), % (n = 288) |
p-value |
|---|---|---|---|---|
| Age* | 60 (52–66) | 60 (53–67) | 63 (52–66) | 0.614 |
| Gender | ||||
| Females | 31.0 | 29.0 | 38.0 | 0.105 |
| Males | 69.0 | 71.0 | 62.0 | |
| Comorbidities | ||||
| Baseline ejection fraction* | 53 (42–61) | 53 (43–61) | 53 (36–60) | 0.209 |
| Systemic hypertension | 68.0 | 71.0 | 60.0 | 0.092 |
| Hypercholesterolemia | 66.0 | 68.0 | 62.0 | 0.334 |
| Angina | 74.0 | 76.0 | 74.0 | 0.855 |
| Myocardial infarction | 46.0 | 74.0 | 51.0 | 0.240 |
| Diabetes mellitus | 46.0 | 50.0 | 39.0 | 0.419 |
| Congestive heart failure | 35.0 | 35.0 | 35.0 | 0.881 |
| Cerebrovascular disease | 6.6 | 8.0 | 3.0 | 0.204 |
| Peripheral vascular disease | 3.5 | 4.0 | 1.0 | 0.284 |
| Surgeries | ||||
| CABG | 72.0 | 77.0 | 59.0 | < 0.001 |
| Valve surgery | 14.3 | 12.0 | 15.0 | |
| Combined CABG and valve surgery | 11.0 | 8.0 | 24.0 | |
| Other surgeries | 2.7 | 3.0 | 3.0 | |
| Operative characteristics | ||||
| Cross-clamp time* | 58 (42–85) | 55 (38–74) | 73 (57–101) | < 0.001 |
| Investigations | ||||
| Baseline hematocrit†(0.35–0.45) | 39.0 ± 5.0 | 39.0 ± 5.0 | 39.0 ± 5.0 | 0.365 |
| TI preoperative, µg/L* | 0.03 (0.01–0.08) | 0.02 (0.01–0.07) | 0.03 (0.01–0.09) | 0.149 |
| TI24 hours postoperative, µg/L* | 2.00 (0.92–5.31) | 1.54 (0.76–2.71) | 11.28 (8.05–20.92) | < 0.001 |
| Transfusion requirements | ||||
| RBC transfusion | 71.1 | 69.0 | 84.0 | 0.006 |
| Platelet transfusion | 23.0 | 22.0 | 30.0 | 0.100 |
CABG: coronary artery bypass graft; RBC: red blood cell; TI: troponin I; TI24: TI levels measured 24 hours.
*Data given as median and interquartile ranges.
†Data given as mean±standard deviation.