Table 1. Clinical characteristics and management according to the occurrence of post discharge bleeding.
Overall cohort (n = 208) | Bleeding (n = 25) | No bleeding (n = 183) | P-value | |
Baseline characteristics | ||||
Age, yrs | 81.9 ± 5 | 82.6 ± 6 | 81.9 ± 4 | 0.538 |
Male | 115 (55.3%) | 16 (64%) | 99 (54.1%) | 0.380 |
Diabetes mellitus | 67 (32.2%) | 5 (20%) | 62 (33.9%) | 0.154 |
Hypertension | 157 (75.5%) | 19 (76%) | 138 (75.4%) | 0.979 |
Dislypidemia | 135 (64.9%) | 13 (52%) | 122 (66.7%) | 0.129 |
Peripheral artery disease | 26 (12.5%) | 5 (20%) | 21 (11.5%) | 0.189 |
Prior stroke | 27 (13%) | 2 (8%) | 25 (13.7%) | 0.390 |
Prior bleeding | 25 (12%) | 4 (16%) | 21 (11.5%) | 0.359 |
Prior myocardial infarction | 30 (14.4%) | 6 (24%) | 24 (13.1%) | 0.154 |
Killip class at admission ≥ 2 | 66 (31.7%) | 6 (24%) | 60 (32.8%) | 0.422 |
Haemoglobin, g/dL | 13.2 ± 6 | 11.6 ± 2 | 13.4 ± 7 | 0.184 |
Creatinine clearance, mL/min | 65 ± 25 | 52 ± 20 | 66 ± 25 | 0.422 |
White blood cell count | 12040 ± 8189 | 11526 ± 3511 | 12111 ± 8690 | 0.740 |
PRECISE-DAPT score | 38 ± 11 | 41 ± 12 | 37 ± 11 | 0.088 |
LVEF | 47 ± 10 | 45 ± 11 | 48 ± 10 | 0.313 |
Multivessel disease | 105 (50.5%) | 14 (56%) | 91 (49.7%) | 0.726 |
Left main disease | 9 (4.3%) | 3 (12%) | 6 (3.3%) | 0.081 |
Geriatric syndromes | ||||
Comorbidity (CI#) | 1.6 ± 1.3 | 1.8 ± 1.6 | 1.6 ± 1.3 | 0.601 |
Disability (BIΔ) | ||||
Independient | 139 (66.8%) | 16 (64%) | 123 (67.2%) | 0.444 |
Mild disability | 50 (24%) | 7 (28%) | 43 (23.5%) | |
Moderate disability | 7 (3.4%) | 1 (4%) | 6 (3.3%) | |
Severe disability | 2 (1%) | 1 (4%) | 1 (0.5%) | |
Completely dependent | 6 (2.9%) | 0(0%) | 6 (3.3%) | |
Frailty (FRAIL scale) | ||||
No | 80 (38.5%) | 8 (32%) | 72 (39.3%) | 0.741 |
Prefrail | 90 (43.3%) | 12 (48%) | 78 (42.6%) | |
Frail | 38 (18.3%) | 5 (20%) | 33 (18%) | |
Cognitive impairment (Pfeiffer test) | ||||
No | 144 (69.2%) | 18 (72%) | 126 (68.9%) | 0.402 |
Mild | 56 (26.9%) | 5 (20%) | 51 (27.9%) | |
Severe | 8 (3.8%) | 2 (8%) | 6 (3.3%) | |
Risk of malnutrition (MNA-SF) | 94 (45.2%) | 13 (52%) | 81 (44.3%) | 0.495 |
Antithrombotic treatment at discharge | ||||
Acetilsalicilic acid | 205 (98.6%) | 25 (100%) | 180 (98.4%) | 0.517 |
Clopidogrel | 183 (88%) | 24 (96%) | 159 (86.9%) | 0.157 |
Ticagrelor | 15 (7.2%) | 1 (4%) | 14 (7.7%) | 0.501 |
Prasugrel | 2 (1%) | 0(0%) | 2 (1.1%) | 0.771 |
Novel oral anticoagulants | 2 (1%) | 0(0%) | 2 (1.1%) | 0.879 |
Vitamin K antagonists | 4 (1.9%) | 0(0%) | 4 (2.2%) | 0.594 |
Data are presented as means ± SD or n (%). LVEF: left ventricle ejection fraction; MNA-SF: mini-nutritional assessment (short form) test. CI: charlson index; BI: barthel index.