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. 2019 Jan 7;12:994. doi: 10.3389/fnins.2018.00994

Table 4.

ROC analysis for differentiating stroke patients from healthy person.

MNI coordinates

Brain regions X Y Z AUC Maximal Youden’s index J Sensitivity Specificity
dALFF at SMA 12 -12 57 0.965 0.861* 95.2% (40/42) 90.9% (50/55)
dReHo at MFG.IL 45 54 18 0.911 0.832 92.9% (39/42) 90.3% (49/55)

By this optimal cut-off point, the dynamic ALFF value of SMA could correctly classify 40 of 42 patients and 50 of 55 healthy subjects, resulted in a sensitivity of 95.2% and a specificity of 90.9.2%. The means of other optimal cut-off point was similar. MNI, Montreal Neurological Institute; AUC, areas under the curves; dALFF, dynamic amplitude of low-frequency fluctuation; dReHo, dynamic regional homogeneity; SMA, supplementary motor area; MFG, middle frontal gyrus; IL, ipsilesional.