Table 1.
Odds ratio of various PPIs from the network meta-analysis for 4-week ulcer healing rate (intention-to-treat data).
| OR | OME | PAN | LAN | RAB | ILA | RAN | FAM | PLA |
|---|---|---|---|---|---|---|---|---|
| OME | 1.0 | 11.241 (0.942, 1.655) | 10.900 (0.634, 1.268) | 10.988 (0.596, 1.638) | 11.463 (0.994, 2.185) | 10.420 (0.348, 0.511) | 10.328 (0.254, 0.424) | 10.152 (0.093, 0.258) |
| PAN | 10.806 (0.604, 1.064) | 1.0 | 10.721 (0.477, 1.091) | 10.802 (0.457, 1.366) | 11.181 (0.732, 1.922) | 10.339 (0.259, 0.441) | 10.265 (0.189, 0.371) | 10.121 (0.072, 0.219) |
| LAN | 11.110 (0.789, 1.576) | 11.386 (0.917, 2.099) | 1.0 | 11.110 (0.615, 1.960) | 11.648 (0.989, 2.702) | 10.471 (0.331, 0.650) | 10.366 (0.251, 0.536) | 10.170 (0.099, 0.303) |
| RAB | 11.013 (0.611, 1.677) | 11.247 (0.732, 2.188) | 10.901 (0.510, 1.626) | 1.0 | 11.457 (0.801, 2.859) | 10.421 (0.261, 0.694) | 10.334 (0.192, 0.563) | 10.153 (0.083, 0.282) |
| ILA | 10.684 (0.458, 1.006) | 10.847 (0.520, 1.366) | 10.607 (0.370, 1.012) | 10.686 (0.350, 1.248) | 1.0 | 10.288 (0.185, 0.445) | 10.225 (0.138, 0.358) | 10.103 (0.055, 0.199) |
| RAN | 12.381 (1.958, 2.876) | 12.949 (2.265, 3.860) | 12.122 (1.539, 3.024) | 12.375 (1.440, 3.841) | 13.472 (2.248, 5.416) | 1.0 | 10.780 (0.621, 0.994) | 10.359 (0.221, 0.614) |
| FAM | 13.052 (2.359, 3.940) | 13.773 (2.694, 5.302) | 12.729 (1.867, 3.979) | 12.993 (1.777, 5.201) | 14.440 (2.794, 7.243) | 11.281 (1.006, 1.611) | 1.0 | 10.455 (0.270, 0.815) |
| PLA | 16.599 (3.877, 10.770) | 18.261 (4.565, 13.940) | 15.891 (3.306, 10.150) | 16.518 (3.549, 12.050) | 19.709 (5.028, 18.250) | 12.787 (1.630, 4.519) | 12.197 (1.227, 3.701) | 1.0 |
Each number is an odds ratio (=row/column), and 95% confidence interval. OME, omeprazole, 20 mg/day; PAN, pantoprazole, 40 mg/day; LAN, lansoprazole, 30 mg/day; RAB, rabeprazole, 20 mg/day; ILA, ilaprazole, 10 mg/day; RAN, ranitidine, 300 mg/day; FAM, famotidine, 40 mg/day; PLA, placebo. Green shading: no significant difference; red shading: significant difference.