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. 2019 Jan 7;10:431. doi: 10.3389/fnagi.2018.00431

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Copyright © 2019 Huh, Choi, Sim and Oh.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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UGS attenuated 6-OHDA-induced motor dysfunctions when co-treated with L-dopa. To evaluate the passive motor function, rotarod test was assessed (A). For hemi-parkinsonian model, it can evaluate the effect of dopamine function via apomorphine-induced rotation tests (B). Values are given as the mean ± S.E.M. (N = 8). The significance of differences was analyzed by one-way ANOVA followed by Bonferroni's Multiple Comparison Test: ^##p < 0.01 and ^###p < 0.001; mean values were significantly different from the sham group. ^*p < 0.05 and ^***p < 0.001; mean values were significantly different from the 6-OHDA group. ^ϕp < 0.05 and ^ϕϕϕ p < 0.001; mean values were significantly different from the 6-OHDA + L-dopa group.