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. 2019 Jan 7;10:431. doi: 10.3389/fnagi.2018.00431

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Copyright © 2019 Huh, Choi, Sim and Oh.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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UGS suppressed the dyskinetic movements in LID mice. 6-OHDA-lesioned mice treated with UGS ameliorates LID over the 21 days treatment period, which differed significantly from the LID groups in all testing sessions. The sum of axial, limb, and oroligual (A), axial (B), forelimb (C), and oroligual (D) AIMs on each testing session were rated following the administration of UGS. Values are given as the mean ± S.E.M. (N = 6). The significance of differences was analyzed by repeated measures of ANOVA with Bonferroni's post hoc tests: ^ϕp < 0.05, ^ϕϕp < 0.01, and ^ϕϕϕp < 0.001; mean values were significantly different from the LID group.