Table I.
Study | Patient age (y), sex | Leukemia subtype | Treatment | Erythroderma at presentation | BSA involved | Patient outcome |
---|---|---|---|---|---|---|
Su et al, 19849∗ | NR | Chronic lymphocytic leukemia | NR | Yes | NR | NR |
Jeong et al, 20097 | 82, male | Small cell variant of T-cell prolymphocytic leukemia | Oral fludarabine and prednisone | Yes | 100% † | Death within 2 wks of chemotherapy initiation |
Raj et al, 20118 | 75, male | Chronic myeloid leukemia | Imatinib | Yes | NR | Resolution within 1 mo of imatinib treatment |
Novoa et al, 20155 | 65, female | Pre–B-cell acute lymphoblastic leukemia | Hospice care | No | 70% | Death |
Current case, 2018 | 50, female | AML | Cytarabine, HSCT | No | 70% | Resolution within 2 wks of cytarabine reinduction |
HSCT, Hematopoietic stem cell transplant; NR, not reported.
Su et al describe 2 cases of erythroderma in patients with CLL as a part of a case series. It is not explicitly described whether the erythroderma was caused by leukemic infiltration of the skin or if it was related to the underlying leukemia.
Jeong et al describe involvement of the whole body although do not explicitly quantify the BSA involvement.