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. 2019 Jan 7;9:1467. doi: 10.3389/fphar.2018.01467

Table 4B.

Risks of hospitalized heart failure associated with cilostazol and NSAIDs use on different window lengths of case period and control period (N = 47,506).

Case period 1-60 days Case period 1-60 days Case period 1-90 days Case period 1-90 days
before index date
before index date
before index date
before index date
Control period 61-120 days Control period 91-150 days Control period 91-180 days Control period 121-210 days
before index date
before index date
before index date
before index date
Adjusted OR 95% C.I. Adjusted OR 95% C.I. Adjusted OR 95% C.I. Adjusted OR 95% C.I.
Cilostazol 1.54 1.27–1.88 1.31 1.12–1.54 1.09 0.93–1.27 1.06 0.92–1.21
NSAIDs 1.51 1.45–1.58 1.45 1.39–1.50 1.33 1.28–1.38 1.26 1.22–1.31

Conditional logistic regression adjusted for important potential time-varying confounding variables including pioglitazone, metformin, sitagliptin, aspirin, angiotensin converting enzyme inhibitors, beta-blockers, calcium channel blockers, diuretics, nitrates, digitalis glycoside, inhaled beta-agonists, inhaled anticholinergics, aminophylline, oral corticosteroids, and systemic antibiotics. Bold values indicate statistical significance; OR, odds ratio; 95% C.I., confidence interval.