Fig. 2.

GLP-1 analogue liraglutide inhibited MCT-induced up-regulation in GLP-1 and DPP-4 expression in lung tissues (a), reversed the increase in right ventricular systolic pressure (RVSP) (b), meanwhile reduces hypertrophy of pulmonary vascular media layer (PAWT) (c), pulmonary vascular fibrosis labeled by Masson trichrome staining (MTS) (d), cross section area (CSA) of cardiomyocytes (e), right ventricle hypertrophy (RV / LV + S) (f), and RV fibrosis labeled by picrosirius red staining (PSR) (g). Data were presented as the mean ± s.e.m. (n = 6–8). *P < 0.05, **P < 0.01, ***P < 0.001