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. 2019 Jan 11;10:25. doi: 10.1186/s13287-018-1123-7

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — In vitro MRI dose response of Nanomag-labelled MSCs encapsulated in 2.5 mg/ml collagen type 1 gel. A and B are MSCs labelled with Nanomag for 1 h and 24 hrs respectively. C and D are MSCs labelled with GET-Nanomag for 1 hr and 24 hrs respectively. For each subfigure, i is the T₂^eff measurement produced from the MRI image and ii is the corresponding T₂^eff plots. Data represents mean T₂^eff values ± s.d. (n = 3) with significance determined by two-way ANOVA statistical test where * is p < 0.05, ** is p < 0.01, *** is p < 0.001 and **** is p < 0.0001