Table 2.
Effect of imatinib and CSF1R on the knee joint diameter (mm) of rheumatoid arthritis rabbits
| Knee joint diameter (change %) | |||
|---|---|---|---|
| 0 | 1 day | 8 days | |
| Sham | 18·8 ± 0·4 | 19·1 ± 0·6 (101·6) | 18·7 ± 0·4 (99·5) |
| NC | 25·0 ± 0·5 | 24·6 ± 0·8 (98·4) | 24·3 ± 0·7 (98·8) |
| Imatinib 1 μM | 25·3 ± 0·8 | 23·6 ± 1·0 (93·3) | 22·5 ± 0·9 (88·9) |
| Imatinib 1 μM+pcDNA3·1‐CSF1R | 25·2 ± 1·1 | 24·8 ± 1·2 (98·4) | 24·7 ± 0·9 (98·0) |
Data are expressed as mean ± standard deviation (s.d.). CSF1R = colony‐stimulating factor receptor‐1; NC = sterile saline group.