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. Author manuscript; available in PMC: 2019 Nov 5.
Published in final edited form as: Mol Pharm. 2018 Oct 17;15(11):5336–5348. doi: 10.1021/acs.molpharmaceut.8b00802

Figure 4. Therapeutic efficacy of sterilized AR-12/MPs against intracellular Salmonella enterica Typhi infection.

Figure 4.

Human monocyte derived macrophages (hMDMs) were treated with acetalated dextran microparticles encapsulating AR-12 (AR-12/MPs; 5 μM) or respective blank acetalated dextran microparticles (Blank MPs; 144 μg), either non-sterilized (red bars), gamma irradiated (blue bars), or ethylene oxide treated (green bars). * indicates significance of p <0.05. Data are presented as mean ± standard deviation of three independent experiments.