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. Author manuscript; available in PMC: 2019 Nov 5.
Published in final edited form as: Mol Pharm. 2018 Oct 17;15(11):5336–5348. doi: 10.1021/acs.molpharmaceut.8b00802

Figure 7. Time-dependent release of endo/lysosomal enzyme, N-acetyl-β-D-glucosaminidase (β-NAG), directed by Ace-DEX MPs and PEI.

Figure 7.

BMDMs were treated with 26% CAC (blue bar) or 55% CAC (green bar) Ace-DEX MPs (0.5 mg/mL) for 1 and 5 days, respectively. PEI (10 μg) treatment for 1 hour was used as a positive control (checkered bar). Cytosolic β-NAG activity was measured with the N-acetyl-β-D-glucosaminidase assay and expressed as enzyme activity normalized to Triton 100-X lysed cells (100% lysed). Values are reported as mean ± SEM. * indicates significance of p < 0.05.