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. 2019 Jan 7;8:645. doi: 10.3389/fonc.2018.00645

Figure 2.

Figure 2

BCL2-family is regulated by the tumor microenvironment. (A) Heat-map of Bcl-2 gene expression profiles for MCL, FL, CLL, and SMZL in function of their tissue localization. Wilcoxon-Mann-Whitney tests. *p < 0.05. (B) Comparison of BCL2L11, PMAIP1, and BCL2L1 gene expression according to their localization. LN, lymph nodes; PB, peripheral blood; BM, bone marrow. Wilcoxon-Mann-Whitney tests. **p < 0.01, ****p < 0.0001. (C) Representation of the individual factor map for the PCA according to the two first dimensions and their respective correlation circle. Colored ellipses are drawn around the mean of the group (= barycenter), with the 95% confidence interval of the mean in the corresponding plan.