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. 2018 Dec 30;2018:4902941. doi: 10.1155/2018/4902941

Table 2.

Breakpoints of 30 antibiotics.

Antimicrobial Agent MIC breakpoints (μg/ml)
Susceptibility Intermediate Resistance
Macrolides CLRa ⩽2 4 8
AZMc ⩽2 4 8
Rifamycins RIFa - - >1
RFBa - - >2
Aminoglycosides STRa - - 5
GENb <=4 8 >=16
KANa - - 4
TOBa ⩽2 4 8
NEOb - - >=10
AMKa ⩽16 32 64
Fluoroquinolones MXFa ⩽1 2 4
CIPa ⩽1 2 4
LVXa ⩽2 4 8
Cephalosporin FOXa ⩽16 32-64 128
CMZd ⩽16 32 64
Tetracyclines TCYb <=4 8 >=16
DOXa ⩽1 2-4 8
MNOa ⩽1 2-4 8
Glycylcycline TGCa ⩽1 2-4 8
Sulfonamides SOXa ⩽38 - 76
Carbapenems IMPa ⩽4 8-16 32
Oxazolidinones LNZa ⩽8 16 32
Lincosamides CLIb <=0.5 1-2 >=4
Penicillins OXAb <=2 - >=4
Polypeptides TECb <=8 16 >=32
VANb <=2 4-8 >=16
Others CFZe - - >1
INHa - - 1
EMBa - - 4
ETHa - - >5

a denotes the breakpoints coming from Susceptibility Testing of Mycobacteria, Nocardia, and Other Aerobic Actinomycetes; Approved Standard–Second Edition. CLSI document M24-A2.

b denotes the breakpoints coming from Performance Standards Antimicrobial Susceptibility Testing-27th Edition. CLSI document M100.

c, d, e denote the breakpoints coming from [1820], respectively.

d, S, susceptible, I, intermediate susceptible, and R, resistant.