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. 2018 Dec 31;2018:2549789. doi: 10.1155/2018/2549789

Figure 2.

Figure 2

IL-10 increases HOXA10 expression via phosphorylation of STAT3. The expression of HOXA10 mRNA and protein was examined by qRT-PCR and western blotting in Ishikawa cells treated with different concentrations of rIL-10 for 12 h ((a) and (c)) or with 100 ng/mL rIL-10 for different times ((b) and (d)). The expression levels of STAT3, p-STAT3, and HOXA10 were examined by western blotting in Ishikawa cells treated with 4.6 μM cryptotanshinone for 24 h, followed by 100 ng/mL rIL-10 for 12 h, or in controls (e).