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Effects of Tat-ATOX1 on ear edema in a TPA-induced mice model. Ears of mice were exposed to TPA (1 μg/ear). Tat-ATOX1 (10 μg) was topically applied to mice ears 1 h after TPA treatment for 3 days. The inhibition of TPA-induced ear edema was analyzed by hematoxylin and eosin immunostaining (A), changes in ear thickness (B), and ear weights (C). Scale bar = 50 μm (top panel) and 25 μm (bottom panel). *P < 0.01, compared to TPA-treated mice.
