Figure 1.

Box plots showing histone lysine methyltransferase (HKMT) mRNA levels in 52 matched prostate cancer tissues (grey) and adjacent normal tissues (brown). Paired t-test was performed to compare the different expression profiles between tumor and adjacent normal tissues. Statistical significance is shown as the p-values by different grayscales of the lower color bars (p>0.05 are specifically shown by * inside the sub-boxes). There was reduced mRNA expression of several genes, including PRDM7, PRDM9, PRDM13, PRDM14, and SMYD1.