Supplementary Table 4.
Summary for association of Gleason score and AR expression with HMTs expression profile.
| Gleason score/HMTs expression (one-way ANOVA, top 11 HMTs were filled with yellow color) | AR/HMTs expression (top 13 significant HMTs with the green padding were also in the same clustering) | |||
|---|---|---|---|---|
| Gene | p.Value | Gene | p.Value | Coefficients |
| ASH1L | 4.49E-01 | ASH1L | 4.94E-155 | 0.871 |
| DOT1L | 7.57E-04 | DOT1L | 1.43E-06 | 0.214 |
| EHMT1 | 2.78E-04 | EHMT1 | 9.08E-46 | 0.579 |
| EHMT2 | 8.27E-01 | EHMT2 | 2.19E-12 | 0.308 |
| EZH1 | 2.11E-02 | EZH1 | 9.07E-01 | 0.005 |
| EZH2 | 1.35E-12 | EZH2 | 1.23E-03 | 0.145 |
| KMT2A | 4.68E-01 | KMT2A | 5.77E-97 | 0.766 |
| KMT2B | 1.40E-01 | KMT2B | 1.24E-128 | 0.832 |
| KMT2C | 3.70E-01 | KMT2C | 5.65E-122 | 0.820 |
| KMT2D | 2.60E-05 | KMT2D | 5.63E-32 | 0.494 |
| KMT2E | 1.92E-01 | KMT2E | 4.56E-105 | 0.785 |
| MECOM | 2.21E-01 | MECOM | 1.31E-06 | 0.215 |
| NSD1 | 5.49E-02 | NSD1 | 8.13E-127 | 0.829 |
| PRDM1 | 3.20E-01 | PRDM1 | 7.06E-13 | 0.315 |
| PRDM10 | 4.92E-04 | PRDM10 | 1.21E-87 | 0.741 |
| PRDM11 | 2.71E-03 | PRDM11 | 6.96E-12 | 0.301 |
| PRDM12 | 5.82E-06 | PRDM12 | 1.80E-01 | 0.060 |
| PRDM13 | 4.62E-01 | PRDM13 | 2.76E-01 | 0.049 |
| PRDM14 | 4.33E-01 | PRDM14 | 7.13E-01 | 0.017 |
| PRDM15 | 5.90E-02 | PRDM15 | 6.48E-04 | 0.152 |
| PRDM16 | 6.83E-01 | PRDM16 | 7.48E-01 | 0.014 |
| PRDM2 | 3.85E-01 | PRDM2 | 2.77E-70 | 0.686 |
| PRDM4 | 4.69E-01 | PRDM4 | 3.72E-54 | 0.620 |
| PRDM5 | 9.29E-02 | PRDM5 | 3.45E-19 | 0.387 |
| PRDM6 | 6.89E-04 | PRDM6 | 4.26E-03 | 0.128 |
| PRDM7 | 3.84E-01 | PRDM7 | 5.38E-03 | 0.125 |
| PRDM8 | 6.63E-05 | PRDM8 | 8.01E-01 | 0.011 |
| PRDM9 | 5.35E-01 | PRDM9 | 7.02E-01 | 0.017 |
| SETD1A | 3.29E-01 | SETD1A | 3.63E-02 | 0.094 |
| SETD1B | 9.31E-03 | SETD1B | 1.11E-44 | 0.573 |
| SETD2 | 2.64E-02 | SETD2 | 3.47E-129 | 0.833 |
| SETD3 | 3.48E-01 | SETD3 | 8.77E-01 | 0.007 |
| SETD4 | 1.29E-03 | SETD4 | 2.56E-22 | 0.417 |
| SETD5 | 2.64E-05 | SETD5 | 6.88E-78 | 0.712 |
| SETD6 | 5.42E-02 | SETD6 | 7.32E-01 | 0.015 |
| SETD7 | 4.45E-01 | SETD7 | 9.24E-106 | 0.787 |
| SETD8 | 2.48E-03 | SETD8 | 5.01E-09 | 0.258 |
| SETDB1 | 1.24E-02 | SETDB1 | 1.60E-13 | 0.323 |
| SETDB2 | 3.50E-01 | SETDB2 | 1.61E-02 | 0.108 |
| SETMAR | 1.63E-01 | SETMAR | 2.40E-34 | 0.511 |
| SMYD1 | 1.97E-01 | SMYD1 | 9.40E-01 | 0.003 |
| SMYD2 | 4.78E-01 | SMYD2 | 2.22E-01 | 0.055 |
| SMYD3 | 5.14E-01 | SMYD3 | 1.14E-09 | 0.269 |
| SMYD4 | 3.06E-01 | SMYD4 | 9.99E-20 | 0.392 |
| SMYD5 | 9.71E-01 | SMYD5 | 8.87E-21 | 0.402 |
| SUV39H1 | 3.77E-01 | SUV39H1 | 4.30E-19 | 0.386 |
| SUV39H2 | 4.21E-02 | SUV39H2 | 1.03E-05 | 0.196 |
| SUV420H1 | 6.57E-03 | SUV420H1 | 3.81E-42 | 0.559 |
| SUV420H2 | 3.88E-04 | SUV420H2 | 7.67E-26 | 0.447 |
| WHSC1 | 2.89E-14 | WHSC1 | 4.06E-31 | 0.488 |
| WHSC1L1 | 5.19E-01 | WHSC1L1 | 6.19E-47 | 0.585 |