Supplementary Table 7A.
Summary of uniivariate analysis of RFS for amplification of 51 HMTs in prostate cancer.
| Gene | p-Value | HR | 95% CI | Count amplification | Count diploid | Count percentage | |
|---|---|---|---|---|---|---|---|
| Lower | Higher | ||||||
| PRDM14 | 0.0081 | 1.860 | 1.185 | 2.919 | 112 | 285 | 28.2 |
| WHSC1L1 | 0.0051 | 2.401 | 1.330 | 4.332 | 51 | 219 | 18.9 |
| EHMT1 | 0.0001 | 3.133 | 1.876 | 5.232 | 46 | 345 | 11.8 |
| PRDM12 | 0.0002 | 3.022 | 1.795 | 5.090 | 44 | 345 | 11.3 |
| SUV420H1 | 0.0075 | 2.390 | 1.336 | 4.273 | 33 | 360 | 8.4 |
| SETDB1 | 0.0031 | 2.860 | 1.543 | 5.303 | 28 | 369 | 7.1 |
| SETD1A | 0.0157 | 2.520 | 1.286 | 4.938 | 23 | 351 | 6.1 |
| SMYD2 | 0.0188 | 2.723 | 1.304 | 5.686 | 21 | 358 | 5.5 |
| PRDM4 | 0.0015 | 3.808 | 1.882 | 7.703 | 20 | 360 | 5.3 |
| PRDM15 | 0.0445 | 2.214 | 1.095 | 4.478 | 18 | 355 | 4.8 |
| SETD1B | 0.0006 | 4.815 | 2.279 | 10.173 | 16 | 355 | 4.3 |
| WHSC1 | 0.0467 | 2.299 | 1.098 | 4.813 | 16 | 362 | 4.2 |
| SETD8 | 0.0100 | 3.722 | 1.596 | 8.682 | 14 | 354 | 3.8 |
| SUV420H2 | 0.0499 | 2.409 | 1.099 | 5.281 | 14 | 371 | 3.6 |
| SMYD5 | 0.0009 | 5.127 | 2.330 | 11.284 | 12 | 363 | 3.2 |
| SMYD1 | 0.0005 | 5.729 | 2.599 | 12.630 | 12 | 367 | 3.2 |
| EHMT2 | 0.0278 | 2.969 | 1.281 | 6.882 | 12 | 372 | 3.1 |
| KMT2B | 0.0311 | 3.242 | 1.300 | 8.084 | 9 | 374 | 2.3 |
| PRDM16 | 0.0029 | 7.508 | 2.674 | 21.079 | 7 | 363 | 1.9 |
| DOT1L | 0.0358 | 3.657 | 1.323 | 10.106 | 5 | 364 | 1.4 |
| PRDM1 | 0.0219 | 9.340 | 2.227 | 39.178 | 2 | 275 | 0.7 |
| SETD3 | 0.2315 | 0.362 | 0.050 | 2.622 | 10 | 358 | 2.7 |
| PRDM7 | 0.3568 | 0.000 | 0.000 | Inf | 4 | 250 | 1.6 |
| SETD4 | 0.0502 | 2.263 | 1.083 | 4.731 | 17 | 365 | 4.5 |
| PRDM8 | 0.0507 | 2.393 | 1.096 | 5.227 | 11 | 373 | 2.9 |
| PRDM13 | 0.0664 | 3.720 | 1.147 | 12.065 | 5 | 269 | 1.8 |
| ASH1L | 0.0749 | 1.998 | 0.993 | 4.017 | 27 | 364 | 6.9 |
| PRDM9 | 0.0840 | 1.953 | 0.971 | 3.926 | 25 | 364 | 6.4 |
| SETD6 | 0.0854 | 4.711 | 1.119 | 19.832 | 6 | 300 | 2.0 |
| PRDM2 | 0.1026 | 9.419 | 1.273 | 69.698 | 2 | 362 | 0.5 |
| NSD1 | 0.1187 | 1.887 | 0.905 | 3.937 | 22 | 367 | 5.7 |
| MECOM | 0.1318 | 1.543 | 0.898 | 2.653 | 62 | 330 | 15.8 |
| SMYD4 | 0.1402 | 3.589 | 0.868 | 14.839 | 5 | 327 | 1.5 |
| EZH2 | 0.1436 | 1.470 | 0.891 | 2.426 | 73 | 318 | 18.7 |
| KMT2E | 0.1859 | 1.418 | 0.857 | 2.347 | 76 | 316 | 19.4 |
| PRDM10 | 0.1868 | 1.649 | 0.821 | 3.311 | 24 | 356 | 6.3 |
| KMT2C | 0.1870 | 1.418 | 0.856 | 2.349 | 74 | 304 | 19.6 |
| SETMAR | 0.1931 | 1.746 | 0.801 | 3.809 | 25 | 353 | 6.6 |
| KMT2A | 0.1991 | 1.674 | 0.802 | 3.494 | 22 | 348 | 5.9 |
| SETD5 | 0.2196 | 1.688 | 0.774 | 3.679 | 25 | 346 | 6.7 |
| SMYD3 | 0.2284 | 1.742 | 0.754 | 4.024 | 21 | 364 | 5.5 |
| PRDM5 | 0.2589 | 1.894 | 0.688 | 5.217 | 10 | 353 | 2.8 |
| SUV39H1 | 0.2972 | 1.975 | 0.620 | 6.296 | 9 | 370 | 2.4 |
| SETD2 | 0.3418 | 1.538 | 0.666 | 3.551 | 24 | 356 | 6.3 |
| PRDM11 | 0.3802 | 1.543 | 0.620 | 3.839 | 16 | 357 | 4.3 |
| SETD7 | 0.6018 | 1.383 | 0.433 | 4.411 | 11 | 371 | 2.9 |
| SETDB2 | 0.6704 | 1.601 | 0.211 | 12.166 | 2 | 232 | 0.9 |
| PRDM6 | 0.6765 | 1.292 | 0.406 | 4.117 | 13 | 354 | 3.5 |
| EZH1 | 0.6774 | 1.570 | 0.216 | 11.403 | 4 | 345 | 1.1 |
| KMT2D | 0.7397 | 1.224 | 0.385 | 3.895 | 11 | 372 | 2.9 |
| SUV39H2 | 0.9204 | 0.943 | 0.295 | 3.016 | 14 | 352 | 3.8 |