Supplementary Table 7B.
Summary of uniivariate analysis of RFS for deletion of 51 HMTs in prostate cancer.
| Gene | p-Value | HR | 95% CI | Count amplification | Count diploid | Count percentage | |
|---|---|---|---|---|---|---|---|
| Lower | Higher | ||||||
| DOT1L | 0.0363 | 2.053 | 1.103 | 3.821 | 30 | 364 | 7.6 |
| EHMT2 | 0.0356 | 2.801 | 1.211 | 6.478 | 15 | 372 | 3.9 |
| PRDM7 | 0.0055 | 1.881 | 1.205 | 2.934 | 145 | 250 | 36.7 |
| SETD4 | 0.0042 | 3.905 | 1.778 | 8.576 | 17 | 365 | 4.5 |
| SETD6 | 0.0016 | 2.161 | 1.364 | 3.423 | 93 | 300 | 23.7 |
| SETDB2 | 0.0082 | 1.833 | 1.164 | 2.886 | 165 | 232 | 41.6 |
| SMYD1 | 0.0102 | 2.847 | 1.409 | 5.756 | 20 | 367 | 5.2 |
| SUV39H2 | 0.0014 | 2.710 | 1.558 | 4.711 | 33 | 352 | 8.6 |
| SUV420H2 | 0.0121 | 2.947 | 1.411 | 6.159 | 14 | 371 | 3.6 |
| WHSC1L1 | 0.0154 | 1.886 | 1.129 | 3.151 | 129 | 219 | 37.1 |
| SETD5 | 0.1644 | 0.481 | 0.151 | 1.531 | 28 | 346 | 7.5 |
| PRDM8 | 0.3963 | 0.573 | 0.140 | 2.341 | 15 | 373 | 3.9 |
| EZH2 | 0.0977 | 0.000 | 0.000 | Inf | 8 | 318 | 2.5 |
| SUV420H1 | 0.1404 | 0.000 | 0.000 | Inf | 6 | 360 | 1.6 |
| SETDB1 | 0.1916 | 0.000 | 0.000 | Inf | 2 | 369 | 0.5 |
| EZH1 | 0.0528 | 1.783 | 1.026 | 3.096 | 50 | 345 | 12.7 |
| PRDM15 | 0.0550 | 2.129 | 1.053 | 4.307 | 26 | 355 | 6.8 |
| PRDM6 | 0.0598 | 2.008 | 1.031 | 3.914 | 32 | 354 | 8.3 |
| SETD1A | 0.0611 | 2.085 | 1.032 | 4.214 | 25 | 351 | 6.6 |
| PRDM1 | 0.0788 | 1.512 | 0.959 | 2.383 | 122 | 275 | 30.7 |
| SETD7 | 0.0805 | 2.162 | 0.989 | 4.727 | 17 | 371 | 4.4 |
| KMT2B | 0.0874 | 2.118 | 0.971 | 4.620 | 16 | 374 | 4.1 |
| PRDM4 | 0.0918 | 2.234 | 0.965 | 5.171 | 19 | 360 | 5.0 |
| PRDM9 | 0.0966 | 2.675 | 0.972 | 7.362 | 10 | 364 | 2.7 |
| PRDM13 | 0.1008 | 1.473 | 0.932 | 2.327 | 125 | 269 | 31.7 |
| SUV39H1 | 0.1021 | 2.042 | 0.937 | 4.449 | 20 | 370 | 5.1 |
| PRDM11 | 0.1118 | 1.846 | 0.916 | 3.719 | 26 | 357 | 6.8 |
| SMYD5 | 0.1304 | 1.855 | 0.884 | 3.892 | 24 | 363 | 6.2 |
| SETD1B | 0.1357 | 1.774 | 0.879 | 3.580 | 28 | 355 | 7.3 |
| SETD8 | 0.1572 | 1.672 | 0.856 | 3.269 | 31 | 354 | 8.1 |
| SMYD3 | 0.1598 | 2.058 | 0.828 | 5.119 | 14 | 364 | 3.7 |
| SETD3 | 0.1602 | 1.595 | 0.860 | 2.956 | 31 | 358 | 8.0 |
| EHMT1 | 0.2166 | 2.283 | 0.712 | 7.313 | 8 | 345 | 2.3 |
| PRDM12 | 0.2324 | 2.215 | 0.690 | 7.111 | 10 | 345 | 2.8 |
| SMYD4 | 0.2552 | 1.373 | 0.808 | 2.334 | 67 | 327 | 17.0 |
| NSD1 | 0.2914 | 1.994 | 0.625 | 6.357 | 10 | 367 | 2.7 |
| PRDM2 | 0.3186 | 1.405 | 0.740 | 2.668 | 35 | 362 | 8.8 |
| PRDM14 | 0.3336 | 3.197 | 0.436 | 23.424 | 2 | 285 | 0.7 |
| KMT2D | 0.3915 | 1.524 | 0.615 | 3.777 | 16 | 372 | 4.1 |
| ASH1L | 0.4391 | 1.635 | 0.513 | 5.211 | 8 | 364 | 2.2 |
| PRDM16 | 0.4450 | 1.327 | 0.658 | 2.676 | 29 | 363 | 7.4 |
| KMT2C | 0.5010 | 0.685 | 0.214 | 2.197 | 21 | 304 | 6.5 |
| SETD2 | 0.6543 | 1.218 | 0.526 | 2.817 | 19 | 356 | 5.1 |
| WHSC1 | 0.7368 | 0.844 | 0.307 | 2.321 | 21 | 362 | 5.5 |
| SETMAR | 0.7739 | 0.865 | 0.314 | 2.382 | 21 | 353 | 5.6 |
| PRDM5 | 0.7968 | 0.904 | 0.415 | 1.971 | 36 | 353 | 9.3 |
| SMYD2 | 0.8241 | 1.111 | 0.447 | 2.762 | 20 | 358 | 5.3 |
| KMT2A | 0.8987 | 1.056 | 0.457 | 2.441 | 29 | 348 | 7.7 |
| PRDM10 | 0.9515 | 0.965 | 0.303 | 3.077 | 19 | 356 | 5.1 |
| MECOM | 0.9671 | 1.025 | 0.318 | 3.305 | 7 | 330 | 2.1 |
| KMT2E | 0.9844 | 0.986 | 0.239 | 4.064 | 7 | 316 | 2.2 |