Supplementary Table 7C.
Summary of univariate analysis of RFS for methylation level of 51 HMTs in prostate cancer.
| Gene | p-Value | HR | 95% CI | |
|---|---|---|---|---|
| Lower | Higher | |||
| PRDM14 | 0.0023 | 2.00E+01 | 2.93E+00 | 1.37E+02 |
| PRDM13 | 0.0181 | 1.17E+01 | 1.57E+00 | 8.66E+01 |
| PRDM6 | 0.0184 | 5.91E+01 | 2.28E+00 | 1.53E+03 |
| PRDM8 | 0.0211 | 1.58E+01 | 1.56E+00 | 1.60E+02 |
| KMT2B | 0.0383 | 1.56E−02 | 3.31E−04 | 7.31E−01 |
| NSD1 | 0.0441 | 3.10E+01 | 1.07E+00 | 8.99E+02 |
| SETDB2 | 0.0572 | 6.91E−02 | 4.83E−03 | 9.87E−01 |
| SETDB1 | 0.0580 | 3.52E−05 | 1.11E−09 | 1.11E+00 |
| SETD4 | 0.0873 | 1.31E+13 | 5.38E−02 | 3.18E+27 |
| EZH2 | 0.1045 | 7.80E−10 | 3.21E−21 | 1.90E+02 |
| KMT2E | 0.1152 | 1.45E+01 | 6.10E−01 | 3.45E+02 |
| PRDM4 | 0.1323 | 4.90E+03 | 1.71E−01 | 1.40E+08 |
| SUV39H1 | 0.1694 | 3.77E+01 | 2.58E−01 | 5.50E+03 |
| PRDM12 | 0.1911 | 1.19E+01 | 3.34E−01 | 4.23E+02 |
| SMYD3 | 0.2266 | 2.15E+04 | 1.62E−03 | 2.87E+11 |
| MECOM | 0.2358 | 4.09E+01 | 1.15E−01 | 1.45E+04 |
| DOT1L | 0.2610 | 3.25E+05 | 2.83E−04 | 3.73E+14 |
| SETD6 | 0.2710 | 4.95E−05 | 3.38E−13 | 7.26E+03 |
| SETD3 | 0.3030 | 1.56E−01 | 4.77E−03 | 5.09E+00 |
| PRDM9 | 0.3091 | 5.09E−01 | 1.39E−01 | 1.86E+00 |
| SETD5 | 0.3255 | 1.49E−01 | 3.32E−03 | 6.66E+00 |
| WHSC1L1 | 0.3297 | 1.86E+02 | 7.11E−03 | 4.86E+06 |
| PRDM1 | 0.3832 | 4.35E+00 | 1.70E−01 | 1.12E+02 |
| SUV420H2 | 0.3911 | 8.48E+07 | 1.16E−09 | 6.20E+24 |
| KMT2D | 0.4038 | 4.02E−04 | 3.62E−12 | 4.46E+04 |
| SUV39H2 | 0.4289 | 6.77E+06 | 1.22E−10 | 3.77E+23 |
| SETD1A | 0.4393 | 9.61E−03 | 6.83E−08 | 1.35E+03 |
| PRDM5 | 0.5427 | 1.69E+00 | 3.16E−01 | 9.06E+00 |
| SMYD2 | 0.5584 | 2.99E+01 | 1.02E−03 | 8.79E+05 |
| SETD7 | 0.5756 | 2.92E−04 | 1.06E−16 | 8.05E+08 |
| EZH1 | 0.6304 | 1.22E+01 | 4.84E−04 | 3.09E+05 |
| PRDM15 | 0.6484 | 6.84E−02 | 6.01E−07 | 7.78E+03 |
| PRDM11 | 0.6665 | 3.32E−01 | 2.30E−03 | 4.80E+01 |
| PRDM10 | 0.7125 | 4.99E−01 | 1.26E−02 | 1.98E+01 |
| SETD2 | 0.7127 | 5.25E−04 | 1.16E−21 | 2.37E+14 |
| SMYD5 | 0.7344 | 2.17E−01 | 3.15E−05 | 1.49E+03 |
| SETD8 | 0.7427 | 2.28E−03 | 7.04E−20 | 7.36E+13 |
| PRDM7 | 0.7496 | 5.91E−01 | 2.37E−02 | 1.48E+01 |
| SMYD1 | 0.7786 | 7.48E−01 | 1.00E−01 | 5.57E+00 |
| ASH1L | 0.8598 | 6.00E−01 | 1.78E−03 | 2.02E+02 |
| SETMAR | 0.8750 | 2.48E+00 | 3.02E−05 | 2.03E+05 |
| EHMT2 | 0.8931 | 1.75E−01 | 1.51E−12 | 2.02E+10 |
| SUV420H1 | 0.8952 | 2.14E+00 | 2.59E−05 | 1.77E+05 |
| WHSC1 | 0.9032 | 7.11E−01 | 2.96E−03 | 1.71E+02 |
| KMT2A | 0.9108 | 2.45E+01 | 1.39E−23 | 4.30E+25 |
| PRDM2 | 0.9111 | 2.29E+00 | 1.16E−06 | 4.51E+06 |
| EHMT1 | NA | NA | NA | NA |
| KMT2C | NA | NA | NA | NA |
| PRDM16 | NA | NA | NA | NA |
| SETD1B | NA | NA | NA | NA |
| SMYD4 | NA | NA | NA | NA |