Table 2.
Demographic characteristics among 472 cases and 492 controls from two U.S. case-control studies of Barrett’s esophagus
| Study of Reflux Disease |
Epidemiology and Incidence of BE |
|||
|---|---|---|---|---|
| Characteristic | Controls N=191 | Cases N=176 | Controls N=301 | Cases N=296 |
| Age, years, mean (SD) | 53.37 (12.08) | 54.75 (12.77) | 62.35 (10.26) | 62.28 (10.71) |
| Sex, n (%) | ||||
| Male | 119 (62.30) | 105 (59.66) | 203 (67.44) | 217 (73.31) |
| Female | 72 (37.70) | 71 (40.34) | 98 (32.56) | 79 (26.69) |
| Race, n (%) | ||||
| White | 175 (91.62) | 157 (89.20) | 256 (85.05) | 256 (86.49) |
| Other | 16 (8.38) | 19 (10.80) | 45 (14.95) | 40 (13.51) |
| BE Segment Length, n (%) | ||||
| <3cm | -- | 139 (84.76) | -- | 109 (43.78) |
| ≥3cm | -- | 25 (15.24) | -- | 140 (56.22) |
| Cigarette Smoking, n (%) | ||||
| Ever | 92 (48.17) | 114 (64.77) | 170 (56.48) | 198 (67.12) |
| Never | 99 (51.83) | 62 (35.23) | 131 (43.52) | 97 (32.88) |
| Gastro-Esophageal Reflux Disease, n (%) | ||||
| Ever | 126 (65.97) | 160 (90.91) | 138 (45.85) | 250 (84.46) |
| Never | 65 (34.03) | 16 (9.09) | 163 (54.15) | 46 (15.54) |
| GERD Frequency, n (%) | ||||
| ≤Weekly | 144 (75.79) | 47 (26.70) | 259 (86.05) | 141 (47.64) |
| >Weekly | 46 (24.21) | 129 (73.30) | 42 (13.95) | 155 (52.36) |
| Proton Pump Inhibitors use, n (%) | ||||
| Ever | 12 (6.32) | 79 (44.89) | 41 (13.71) | 201 (68.37) |
| Never | 178 (93.68) | 97 (55.11) | 258 (86.29) | 93 (31.63) |
| Body Mass Index (kg/m2) | ||||
| <25 | 62 (33.33) | 35 (20.12) | 70 (23.25) | 59 (19.93) |
| 25-<30 | 76 (40.86) | 73 (41.95) | 111 (36.88) | 121 (40.88) |
| ≥30 | 48 (25.81) | 66 (37.93) | 120 (39.87) | 116 (39.19) |
| Fruit/vegetable Intake, servings/daya, median (SD) | 1.71 (1.49) | 1.71 (1.43) | 4.40 (2.92) | 3.65 (2.54) |
a
Based on study-specific serving sizes and study-specific food frequency questionnaires.
Missing values (N): GERD frequency (1), smoking (1), PPI (5), BMI (7), fruit/vegetable intake (32), BE segment length (59).