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(A) VIR was significantly associated with the T-stage (P = 0.005), being higher in T3/4 tumors compared with T1/T2-tumors. VIR-high was significantly more frequent in left-sided CRCs (P = 0.024). (B) EIR was significantly associated with the T-stage, lymph node metastasis (N-category), distant metastasis (M-category), lymphatic invasion (L-category) and UICC stage (not shown).
