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. 2018 Dec 25;9(101):37497–37508. doi: 10.18632/oncotarget.26490

Figure 4. Kaplan-Meier curves.

Figure 4

Kaplan-Meier curves depict significant correlations between the expression of the insulin receptor in tumor cells (EIR) and overall (A; P = 0.007) and tumor specific survival (B; P = 0.011) in the entire cohort. Furthermore, patients without epithelial IR expression (EIR-negative) showed a worse prognosis in UICC stage II CRC with respect to overall (C; P = 0.043) and tumor specific survival (D; P = 0.045). Vascular IR expression (VIR) was not associated with overall (E, P = 0.414) or tumor specific survival (F, P = 0.205).