Table 3.
Univariate and multivariate Cox proportional hazards regression analysis of SNHG6 for relapse-free survival in CRC patients
| Variants | Univariate analysis
|
Multivariate analysis
|
||||
|---|---|---|---|---|---|---|
| HR | 95% CI | P-value | HR | 95% CI | P-value | |
|
| ||||||
| Age (≥60 vs <60) | 1.43 | 0.69–2.95 | 0.340 | |||
| Gender (female vs male) | 0.88 | 0.46–1.69 | 0.700 | |||
| Tumor location (rectum vs colon) | 0.90 | 0.43–1.91 | 0.790 | |||
| Distant metastasis (yes vs no) | 1.97 | 0.76–5.08 | 0.161 | |||
| Venous invasion (yes vs no) | 1.11 | 0.27–4.64 | 0.889 | |||
| Tumor size (>5 cm vs ≤5 cm) | 2.07 | 1.06–4.05 | 0.034 | 1.09 | 0.50–2.36 | 0.820 |
| Lymphatic invasion (yes vs no) | 5.20 | 2.35–11.52 | 0.000 | 4.23 | 1.77–10.08 | 0.001 |
| TNM stage (III/IV vs I/II) | 1.72 | 0.90–3.28 | 0.103 | |||
| SNHG6 (high vs low) | 3.18 | 1.45–6.98 | 0.004 | 2.70 | 1.17–6.20 | 0.020 |
Note: Bold values represent P<0.05.
Abbreviations: CRC, colorectal cancer; RFS, relapse-free survival.