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. 2018 Dec 19;10(1):27–33. doi: 10.1021/acsmedchemlett.8b00315

Figure 2.

Figure 2

Effect of 6e on KCNQ2 and KCNQ4 channels. (A,B) Representative current traces of KCNQ2 (A) and KCNQ4 (B) channels activated by 6e using different drug concentrations as indicated are shown. (C) Histogram plotting 6e and RTG effect on KCNQ2 currents measured at −10 mV (n ≥ 4). (D) Concentration–response relationships of 6e on homomeric KCNQ4 currents. The Hill coefficient was 0.33.