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. 2018 Dec 19;10(1):27–33. doi: 10.1021/acsmedchemlett.8b00315

Table 3. Potency (EC50, μM) of RTG, 8g, 10g, and 13 against KCNQ4, KCNQ5, and KCNQ2.

  RTG 8g 10g 13
KCNQ4 5.90 ± 0.18 2.03 ± 0.14 0.78 ± 0.14 1.42 ± 0.04
KCNQ5 3.45 ± 0.28 2.43 ± 0.17 1.68 ± 0.12 1.37 ± 0.11
KCNQ2 2.17 ± 0.07 >30 >30 >30