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X-ray structure of DMXAA molecules bound to mouse STING in the “closed” conformation (PDB 4LOL).15 STING protein is colored green, and DMXAA is shown in blue sticks. Intermolecular interactions between DMXAA and Thr-262 and Thr-266 are indicated by black dashes. There is also a salt bridge between the DMXAA carboxylate group and Arg-237 (not shown; corresponds to Arg-238 in human STING).
