Numerical simulation of (a) CO32- concentration as a function of the ratio of [CO3−•] and [HO•] oxidized tryptophan concentration, where the amino acid tryptophan is taken as a model for reactions of amino acids with a target protein; (b) CO3−• and other related species as a function of time with 700 mM CO32-. Different curves, as denoted by different colors, are plotted on a log scale to represent time-dependent concentrations of each components. The products produced by oxidation of CO3−• and HO• are colored in orange and dark blue, respectively. The dashed line represents the time at which the chemistry is optimized (i.e., largely complete in 10 μs).